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Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM26116
Substrate
n/a
Meas. Tech.
ChEMBL_104646 (CHEMBL712892)
IC50
7800±n/a nM
Citation
 Buynak, JD; Chen, H; Vogeti, L; Gadhachanda, VR; Buchanan, CA; Palzkill, T; Shaw, RW; Spencer, J; Walsh, TR Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases. Bioorg Med Chem Lett 14:1299-304 (2004) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM26116
Synonyms:
CHEMBL284104 | Dipicolinate | pyridine carboxylate, 6d | pyridine-2,6-dicarboxylic acid
Type:
Small organic molecule
Emp. Form.:
C7H5NO4
Mol. Mass.:
167.1189
SMILES:
OC(=O)c1cccc(n1)C(O)=O
Structure:
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