Reaction Details Report a problem with these data
Target
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Ligand
BDBM50141276
Substrate
n/a
Meas. Tech.
ChEBML_100169
IC50
>5000±n/a nM
Citation
 Gong, B; Hong, F; Kohm, C; Bonham, L; Klein, P Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-beta. Bioorg Med Chem Lett 14:1455-9 (2004) [PubMed]  Article 
Target
Name:
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Synonyms:
1-acylglycerol-3-phosphate O-acyltransferase beta | AGPAT2 | PLCB_HUMAN
Type:
PROTEIN
Mol. Mass.:
30924.09
Organism:
Homo sapiens (Human)
Description:
ChEMBL_321473
Residue:
278
Sequence:
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
  
Inhibitor
Name:
BDBM50141276
Synonyms:
CHEMBL284685 | N-[4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-2-methylamino-acetamide
Type:
Small organic molecule
Emp. Form.:
C16H13Cl2N3O2
Mol. Mass.:
350.199
SMILES:
CNCC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(Cl)ccc2o1
Structure:
Search PDB for entries with ligand similarity: