Reaction Details Report a problem with these data
Target
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Ligand
BDBM50141296
Substrate
n/a
Meas. Tech.
ChEBML_100169
IC50
70.0±n/a nM
Citation
 Gong, B; Hong, F; Kohm, C; Bonham, L; Klein, P Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-beta. Bioorg Med Chem Lett 14:1455-9 (2004) [PubMed]  Article 
Target
Name:
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Synonyms:
1-acylglycerol-3-phosphate O-acyltransferase beta | AGPAT2 | PLCB_HUMAN
Type:
PROTEIN
Mol. Mass.:
30924.09
Organism:
Homo sapiens (Human)
Description:
ChEMBL_321473
Residue:
278
Sequence:
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
  
Inhibitor
Name:
BDBM50141296
Synonyms:
CHEMBL32731 | N-(3-Benzothiazol-2-yl-4-methyl-phenyl)-2-cyano-acetamide
Type:
Small organic molecule
Emp. Form.:
C17H13N3OS
Mol. Mass.:
307.37
SMILES:
Cc1ccc(NC(=O)CC#N)cc1-c1nc2ccccc2s1
Structure:
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