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Target
Melatonin receptor type 1B
Ligand
BDBM50575512
Substrate
n/a
Meas. Tech.
ChEMBL_2125496 (CHEMBL4834841)
EC50
0.520000±n/a nM
Citation
 Ferreira, MA; Azevedo, H; Mascarello, A; Segretti, ND; Russo, E; Russo, V; Guimarães, CRW Discovery of  J Med Chem 64:1904-1929 (2021) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50575512
Synonyms:
CHEMBL4854625
Type:
Small organic molecule
Emp. Form.:
C13H17N3O3
Mol. Mass.:
263.2924
SMILES:
COc1nc2ccc(OC)cc2n1CCNC(C)=O
Structure:
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