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Target
Microtubule-associated proteins 1A/1B light chain 3A
Ligand
BDBM50575791
Substrate
n/a
Meas. Tech.
ChEMBL_2126002 (CHEMBL4835347)
Ki
75000±n/a nM
Citation
 Hartmann, M; Huber, J; Kramer, JS; Heering, J; Pietsch, L; Stark, H; Odadzic, D; Bischoff, I; Fürst, R; Schröder, M; Akutsu, M; Chaikuad, A; Dötsch, V; Knapp, S; Biondi, RM; Rogov, VV; Proschak, E Demonstrating Ligandability of the LC3A and LC3B Adapter Interface. J Med Chem 64:3720-3746 (2021) [PubMed]  Article 
Target
Name:
Microtubule-associated proteins 1A/1B light chain 3A
Synonyms:
Autophagy-related protein LC3 A | Autophagy-related ubiquitin-like modifier LC3 A | MAP1 light chain 3-like protein 1 | MAP1A/MAP1B LC3 A | MAP1A/MAP1B light chain 3 A | MAP1LC3A | MLP3A_HUMAN | Microtubule-associated protein 1 light chain 3 alpha | Microtubule-associated proteins 1A/1B light chain 3A
Type:
PROTEIN
Mol. Mass.:
14275.82
Organism:
Homo sapiens
Description:
ChEMBL_120482
Residue:
121
Sequence:
MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF
  
Inhibitor
Name:
BDBM50575791
Synonyms:
CHEMBL4848538
Type:
Small organic molecule
Emp. Form.:
C24H19NO5
Mol. Mass.:
401.4114
SMILES:
Oc1ccc2c(O)c(NC(=O)c3cccc(CCc4ccccc4)c3)c(=O)oc2c1
Structure:
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