Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50580517
Substrate
n/a
Meas. Tech.
ChEMBL_2148501 (CHEMBL5032899)
Ki
19±n/a nM
Citation
 Hagenow, S; Affini, A; Pioli, EY; Hinz, S; Zhao, Y; Porras, G; Namasivayam, V; Müller, CE; Lin, JS; Bezard, E; Stark, H Adenosine A J Med Chem 64:8246-8262 (2021) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50580517
Synonyms:
CHEMBL5084903
Type:
Small organic molecule
Emp. Form.:
C25H28N4O
Mol. Mass.:
400.516
SMILES:
Nc1nc-2c(Cc3ccc(OCCCN4CCCCC4)cc-23)c(n1)-c1ccccc1
Structure:
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