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Target
Trace amine-associated receptor 1
Ligand
BDBM50581608
Substrate
n/a
Meas. Tech.
ChEMBL_2151755 (CHEMBL5036217)
EC50
3.5±n/a nM
Citation
 Heffernan, MLR; Herman, LW; Brown, S; Jones, PG; Shao, L; Hewitt, MC; Campbell, JE; Dedic, N; Hopkins, SC; Koblan, KS; Xie, L Ulotaront: A TAAR1 Agonist for the Treatment of Schizophrenia. ACS Med Chem Lett 13:92-98 (2022) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM50581608
Synonyms:
CHEMBL5082760
Type:
Small organic molecule
Emp. Form.:
C8H11NOS
Mol. Mass.:
169.244
SMILES:
NC[C@@H]1OCCc2ccsc12 |r|
Structure:
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