Reaction Details Report a problem with these data
Target
Alpha-synuclein
Ligand
BDBM50582849
Substrate
n/a
Meas. Tech.
ChEMBL_2155874 (CHEMBL5040534)
Kd
320±n/a nM
Citation
 Bian, J; Liu, YQ; He, J; Lin, X; Qiu, CY; Yu, WB; Shen, Y; Zhu, ZY; Ye, DY; Wang, J; Chu, Y Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands. Eur J Med Chem 226:0 (2021) [PubMed]  Article 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50582849
Synonyms:
CHEMBL5080710
Type:
Small organic molecule
Emp. Form.:
C19H17N3O2
Mol. Mass.:
319.3572
SMILES:
COc1ccc(\C=C\c2ccccc2NC(=O)c2ccn[nH]2)cc1
Structure:
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