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Target
Dipeptidyl peptidase 2
Ligand
BDBM50151791
Substrate
n/a
Meas. Tech.
ChEMBL_305345 (CHEMBL832725)
IC50
67630±n/a nM
Citation
 Xu, J; Ok, HO; Gonzalez, EJ; Colwell, LF; Habulihaz, B; He, H; Leiting, B; Lyons, KA; Marsilio, F; Patel, RA; Wu, JK; Thornberry, NA; Weber, AE; Parmee, ER Discovery of potent and selective beta-homophenylalanine based dipeptidyl peptidase IV inhibitors. Bioorg Med Chem Lett 14:4759-62 (2004) [PubMed]  Article 
Target
Name:
Dipeptidyl peptidase 2
Synonyms:
DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase
Type:
Protein
Mol. Mass.:
54339.29
Organism:
Homo sapiens (Human)
Description:
Q9UHL4
Residue:
492
Sequence:
MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL
  
Inhibitor
Name:
BDBM50151791
Synonyms:
(R)-3-Amino-4-(4-fluoro-phenyl)-1-thiazolidin-3-yl-butan-1-one | CHEMBL363879
Type:
Small organic molecule
Emp. Form.:
C13H17FN2OS
Mol. Mass.:
268.35
SMILES:
N[C@@H](CC(=O)N1CCSC1)Cc1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: