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Target
Adenosine receptor A1
Ligand
BDBM50585024
Substrate
n/a
Meas. Tech.
ChEMBL_2161284 (CHEMBL5046034)
Ki
722±n/a nM
Citation
 Tang, ML; Wen, ZH; Wang, JH; Wang, ML; Zhang, H; Liu, XH; Jin, L; Chang, J Discovery of Pyridone-Substituted Triazolopyrimidine Dual A ACS Med Chem Lett 13:436-442 (2022) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50585024
Synonyms:
CHEMBL5091575
Type:
Small organic molecule
Emp. Form.:
C15H14N8O
Mol. Mass.:
322.3247
SMILES:
Cn1ccc(n1)-c1nc2c(cnc(N)n2n1)-c1ccc(=O)n(C)c1
Structure:
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