Reaction Details Report a problem with these data
Target
Protein S100-B
Ligand
BDBM50154221
Substrate
n/a
Meas. Tech.
ChEMBL_302128 (CHEMBL841752)
Kd
18300±n/a nM
Citation
 Markowitz, J; Chen, I; Gitti, R; Baldisseri, DM; Pan, Y; Udan, R; Carrier, F; MacKerell, AD; Weber, DJ Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction. J Med Chem 47:5085-93 (2004) [PubMed]  Article 
Target
Name:
Protein S100-B
Synonyms:
S-100 protein beta chain | S100B | S100B_HUMAN
Type:
PROTEIN
Mol. Mass.:
10701.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_947124
Residue:
92
Sequence:
MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
  
Inhibitor
Name:
BDBM50154221
Synonyms:
5-((2E)-2-{[5-(3-carboxy-4-chlorophenyl)-2-furyl]methylene}hydrazino)-2-chlorobenzoic acid | CHEMBL433966
Type:
Small organic molecule
Emp. Form.:
C19H12Cl2N2O5
Mol. Mass.:
419.215
SMILES:
OC(=O)c1cc(ccc1Cl)N=NCc1ccc(o1)-c1ccc(Cl)c(c1)C(O)=O |w:10.10|
Structure:
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