Reaction Details Report a problem with these data
Target
Protein S100-B
Ligand
BDBM50154226
Substrate
n/a
Meas. Tech.
ChEMBL_302128 (CHEMBL841752)
Kd
120000±n/a nM
Citation
 Markowitz, J; Chen, I; Gitti, R; Baldisseri, DM; Pan, Y; Udan, R; Carrier, F; MacKerell, AD; Weber, DJ Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction. J Med Chem 47:5085-93 (2004) [PubMed]  Article 
Target
Name:
Protein S100-B
Synonyms:
S-100 protein beta chain | S100B | S100B_HUMAN
Type:
PROTEIN
Mol. Mass.:
10701.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_947124
Residue:
92
Sequence:
MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
  
Inhibitor
Name:
BDBM50154226
Synonyms:
5-{[1,3-Dioxo-2-(2,4,6-trimethyl-phenyl)-2,3-dihydro-1H-isoindole-5-carbonyl]-amino}-isophthalic acid | CHEMBL187059
Type:
Small organic molecule
Emp. Form.:
C26H20N2O7
Mol. Mass.:
472.4462
SMILES:
Cc1cc(C)c(N2C(=O)c3ccc(cc3C2=O)C(=O)Nc2cc(cc(c2)C(O)=O)C(O)=O)c(C)c1
Structure:
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