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Target
Carbonic anhydrase 5A, mitochondrial
Ligand
BDBM50027795
Substrate
n/a
Meas. Tech.
ChEMBL_305668 (CHEMBL827937)
IC50
>100000±n/a nM
Citation
 Innocenti, A; Antel, J; Wurl, M; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives. Bioorg Med Chem Lett 14:5703-7 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 5A, mitochondrial
Synonyms:
CA-VA | CA5 | CA5A | CAH5A_HUMAN | Carbonate dehydratase VA | Carbonic Anhydrase VA | Carbonic anhydrase 5A (CA VA) | Carbonic anhydrase 5A, mitochondrial | Carbonic anhydrase 5A, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VA (CA VA)
Type:
Enzyme
Mol. Mass.:
34755.54
Organism:
Homo sapiens (Human)
Description:
Human (cloned) isozyme
Residue:
305
Sequence:
MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS
  
Inhibitor
Name:
BDBM50027795
Synonyms:
1N-amino(imino)methyl-4-amino-1-benzenesulfonamide | 2-[(dioxidosulfanyl)amino]-1,9-dihydro-6H-purin-6-one[sulfaguanine] | 4-Amino-N-diaminomethylene-benzenesulfonamide | 4-amino-N-[(E)-amino(imino)methyl]benzenesulfonamide | 4-amino-N-[(Z)-amino(imino)methyl]benzenesulfonamide | CHEMBL338802 | Sulfaguanidine | sulphaguanidine
Type:
Small organic molecule
Emp. Form.:
C7H10N4O2S
Mol. Mass.:
214.245
SMILES:
NC(=N)NS(=O)(=O)c1ccc(N)cc1
Structure:
Search PDB for entries with ligand similarity: