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Target
Capsid protein
Ligand
BDBM50586562
Substrate
n/a
Meas. Tech.
ChEMBL_2169046 (CHEMBL5054105)
IC50
2800±n/a nM
Citation
 Kuduk, SD; Stoops, B; Lam, AM; Espiritu, C; Vogel, R; Lau, V; Klumpp, K; Flores, OA; Hartman, GD Oxadiazepinone HBV capsid assembly modulators. Bioorg Med Chem Lett 52:0 (2021) [PubMed]  Article 
Target
Name:
Capsid protein
Synonyms:
Core antigen
Type:
PROTEIN
Mol. Mass.:
26278.39
Organism:
Hepatitis B virus
Description:
ChEMBL_450484
Residue:
230
Sequence:
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM50586562
Synonyms:
CHEMBL4781128
Type:
Small organic molecule
Emp. Form.:
C20H19N3O2
Mol. Mass.:
333.3838
SMILES:
O=C(COc1ccccc1)N1CCc2[nH]nc(c2C1)-c1ccccc1
Structure:
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