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Target
Transient receptor potential cation channel subfamily V member 3
Ligand
BDBM50061117
Substrate
n/a
Meas. Tech.
ChEMBL_2184547 (CHEMBL5096629)
EC50
5300±n/a nM
Citation
 Sampson, PB Phytocannabinoid Pharmacology: Medicinal Properties of  J Nat Prod 84:142-160 (2021) [PubMed] 
Target
Name:
Transient receptor potential cation channel subfamily V member 3
Synonyms:
TRPV3 | TRPV3_HUMAN | Transient receptor potential cation channel subfamily V member 3 (TRPV3) | Vanilloid receptor-like 3
Type:
Enzyme
Mol. Mass.:
90635.51
Organism:
Homo sapiens (Human)
Description:
Q8NET8
Residue:
790
Sequence:
MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTSPPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTDFNKIQDSSRNNSKTTLNAFEEVEEFPETSV
  
Inhibitor
Name:
BDBM50061117
Synonyms:
6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol | 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol (Cannabinol) | 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol(Cannabinol) | CANNABINOL | CBN | CHEMBL74415
Type:
Small organic molecule
Emp. Form.:
C21H26O2
Mol. Mass.:
310.4299
SMILES:
CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1
Structure:
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