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Target
Stimulator of interferon genes protein
Ligand
BDBM50587692
Substrate
n/a
Meas. Tech.
ChEMBL_2184612 (CHEMBL5096694)
Kd
522000±n/a nM
Citation
 Liu, Y; Lu, X; Qin, N; Qiao, Y; Xing, S; Liu, W; Feng, F; Liu, Z; Sun, H STING, a promising target for small molecular immune modulator: A review. Eur J Med Chem 211:0 (2021) [PubMed] 
Target
Name:
Stimulator of interferon genes protein
Synonyms:
Endoplasmic reticulum interferon stimulator | Eris | MMITA | Mediator of IRF3 activation | Mita | Mpys | STING_MOUSE | Stimulator of interferon genes protein | Sting | Sting1 | Synonyms=Eris | Tmem173 | Transmembrane protein 173 | mSTING
Type:
PROTEIN
Mol. Mass.:
42834.49
Organism:
Mus musculus
Description:
ChEMBL_119061
Residue:
378
Sequence:
MPYSNLHPAIPRPRGHRSKYVALIFLVASLMILWVAKDPPNHTLKYLALHLASHELGLLLKNLCCLAEELCHVQSRYQGSYWKAVRACLGCPIHCMAMILLSSYFYFLQNTADIYLSWMFGLLVLYKSLSMLLGLQSLTPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCILEYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTDGNSFSLSQEVLRHIRQEEKEEVTMNAPMTSVAPPPSVLSQEPRLLISGMDQPLPLRTDLI
  
Inhibitor
Name:
BDBM50587692
Synonyms:
CHEMBL5191485
Type:
Small organic molecule
Emp. Form.:
C17H14O5
Mol. Mass.:
298.2901
SMILES:
Cc1c(O)cc2c(oc3c(CC(O)=O)cccc3c2=O)c1C
Structure:
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