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Target
Stimulator of interferon genes protein
Ligand
BDBM50587699
Substrate
n/a
Meas. Tech.
ChEMBL_2184643 (CHEMBL5096725)
IC50
3420±n/a nM
Citation
 Liu, Y; Lu, X; Qin, N; Qiao, Y; Xing, S; Liu, W; Feng, F; Liu, Z; Sun, H STING, a promising target for small molecular immune modulator: A review. Eur J Med Chem 211:0 (2021) [PubMed] 
Target
Name:
Stimulator of interferon genes protein
Synonyms:
Endoplasmic reticulum interferon stimulator | Eris | MMITA | Mediator of IRF3 activation | Mita | Mpys | STING_MOUSE | Stimulator of interferon genes protein | Sting | Sting1 | Synonyms=Eris | Tmem173 | Transmembrane protein 173 | mSTING
Type:
PROTEIN
Mol. Mass.:
42834.49
Organism:
Mus musculus
Description:
ChEMBL_119061
Residue:
378
Sequence:
MPYSNLHPAIPRPRGHRSKYVALIFLVASLMILWVAKDPPNHTLKYLALHLASHELGLLLKNLCCLAEELCHVQSRYQGSYWKAVRACLGCPIHCMAMILLSSYFYFLQNTADIYLSWMFGLLVLYKSLSMLLGLQSLTPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCILEYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTDGNSFSLSQEVLRHIRQEEKEEVTMNAPMTSVAPPPSVLSQEPRLLISGMDQPLPLRTDLI
  
Inhibitor
Name:
BDBM50587699
Synonyms:
CHEMBL5177139
Type:
Small organic molecule
Emp. Form.:
C25H33Cl2N5O6
Mol. Mass.:
570.465
SMILES:
[H][C@@]12[C@H](Cl)[C@H](Cl)CN1C(=O)[C@@H](CC)NC(=O)C[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC)NC2=O)c1ccccc1 |r|
Structure:
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