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Target
Proto-oncogene tyrosine-protein kinase Src
Ligand
BDBM50587782
Substrate
n/a
Meas. Tech.
ChEMBL_2185236 (CHEMBL5097318)
Kd
0.280000±n/a nM
Citation
 Lee, S; Kim, J; Jo, J; Chang, JW; Sim, J; Yun, H Recent advances in development of hetero-bivalent kinase inhibitors. Eur J Med Chem 216:0 (2021) [PubMed] 
Target
Name:
Proto-oncogene tyrosine-protein kinase Src
Synonyms:
Proto-oncogene c-Src | SRC | SRC_CHICK | Tyrosine-protein kinase SRC | c-Src | p60-Src | p60c-src | pp60c-src
Type:
Tyr protein kinase
Mol. Mass.:
60015.36
Organism:
Gallus gallus (Chicken)
Description:
P00523
Residue:
533
Sequence:
MGSSKSKPKDPSQRRRSLEPPDSTHHGGFPASQTPNKTAAPDTHRTPSRSFGTVATEPKLFGGFNTSDTVTSPQRAGALAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
  
Inhibitor
Name:
BDBM50587782
Synonyms:
CHEMBL5209202
Type:
Small organic molecule
Emp. Form.:
C81H99ClN20O22
Mol. Mass.:
1740.227
SMILES:
CCC(C)[C@@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(C)=O)C(=O)N[C@H](Cc1ccc(NC(=O)CCCCCn2cc(nn2)-c2ccc(cc2)-n2nc(-c3ccc(Cl)cc3)c3c(N)ncnc23)cc1)C(=O)NCC(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C)C(N)=O |r|
Structure:
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