Reaction Details Report a problem with these data
Target
Cytochrome c oxidase subunit 2
Ligand
BDBM50587909
Substrate
n/a
Meas. Tech.
ChEMBL_2185748 (CHEMBL5097830)
IC50
7.2±n/a nM
Citation
 Neha, K; Wakode, S Contemporary advances of cyclic molecules proposed for inflammation. Eur J Med Chem 221:0 (2021) [PubMed] 
Target
Name:
Cytochrome c oxidase subunit 2
Synonyms:
COII | COX2 | COX2_SHEEP | COXII | Cytochrome c oxidase polypeptide II | MT-CO2 | MTCO2
Type:
PROTEIN
Mol. Mass.:
25987.16
Organism:
Ovis aries
Description:
ChEMBL_662815
Residue:
227
Sequence:
MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILIMIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTVRMLISSEDVLPSWAVPSLGLKTDAIPGRLNQTTLMSTRPGLFYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML
  
Inhibitor
Name:
BDBM50587909
Synonyms:
CHEMBL5174073
Type:
Small organic molecule
Emp. Form.:
C21H19ClN2O3
Mol. Mass.:
382.84
SMILES:
COc1ccc2cc(ccc2c1)C(C)C(=O)O\N=C(/N)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: