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Target
Cytochrome c oxidase subunit 2
Ligand
BDBM50587914
Substrate
n/a
Meas. Tech.
ChEMBL_2185778 (CHEMBL5097860)
IC50
110±n/a nM
Citation
 Neha, K; Wakode, S Contemporary advances of cyclic molecules proposed for inflammation. Eur J Med Chem 221:0 (2021) [PubMed] 
Target
Name:
Cytochrome c oxidase subunit 2
Synonyms:
COII | COX2 | COX2_SHEEP | COXII | Cytochrome c oxidase polypeptide II | MT-CO2 | MTCO2
Type:
PROTEIN
Mol. Mass.:
25987.16
Organism:
Ovis aries
Description:
ChEMBL_662815
Residue:
227
Sequence:
MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILIMIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTVRMLISSEDVLPSWAVPSLGLKTDAIPGRLNQTTLMSTRPGLFYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML
  
Inhibitor
Name:
BDBM50587914
Synonyms:
CHEMBL5200917
Type:
Small organic molecule
Emp. Form.:
C23H17N3O4
Mol. Mass.:
399.3988
SMILES:
C\C(=N\Nc1ccc(cc1)C(O)=O)c1cccc(c1)N1C(=O)c2ccccc2C1=O
Structure:
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