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Target
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Ligand
BDBM50589383
Substrate
n/a
Meas. Tech.
ChEMBL_2193441 (CHEMBL5105801)
IC50
13480±n/a nM
Citation
 Lee, B; Gyu Kim, D; Mi Kim, Y; Kim, S; Choi, I Discovery of benzodioxane analogues as lead candidates of AIMP2-DX2 inhibitors. Bioorg Med Chem Lett 73:0 (2022) [PubMed] 
Target
Name:
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Synonyms:
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 | JTV1 | Multisynthase complex auxiliary component p38 | Protein JTV-1 | AIMP2_HUMAN | AIMP2 | JTV1
Type:
PROTEIN
Mol. Mass.:
35355.45
Organism:
Human
Description:
ChEMBL_119035
Residue:
320
Sequence:
MPMYQVKPYHGGGAPLRVELPTCMYRLPNVHGRSYGPAPGAGHVQEESNLSLQALESRQDDILKRLYELKAAVDGLSKMIQTPDADLDVTNIIQADEPTTLTTNALDLNSVLGKDYGALKDIVINANPASPPLSLLVLHRLLCEHFRVLSTVHTHSSVKSVPENLLKCFGEQNKKQPRQDYQLGFTLIWKNVPKTQMKFSIQTMCPIEGEGNIARFLFSLFGQKHNAVNATLIDSWVDIAIFQLKEGSSKEKAAVFRSMNSALGKSPWLAGNELTVADVVLWSVLQQIGGCSVTVPANVQRWMRSCENLAPFNTALKLLK
  
Inhibitor
Name:
BDBM50589383
Synonyms:
CHEMBL5186158
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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