Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50590723
Substrate
n/a
Meas. Tech.
ChEMBL_2197638 (CHEMBL5110154)
Ki
29000±n/a nM
Citation
 Das, A; Dasgupta, S; Pathak, T Crescent-shaped meta-substituted benzene derivatives as a new class of non-nucleoside ribonuclease A inhibitors. Bioorg Med Chem 71:0 (2022) [PubMed] 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50590723
Synonyms:
CHEMBL5174669
Type:
Small organic molecule
Emp. Form.:
C14H22N6O10S2
Mol. Mass.:
498.489
SMILES:
O[C@H]1[C@H](COCc2cn(CCS(O)(=O)=O)nn2)O[C@H](Cn2cc(CS(O)(=O)=O)nn2)[C@H]1O |r|
Structure:
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