Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50590795
Substrate
n/a
Meas. Tech.
ChEMBL_2197773 (CHEMBL5110289)
Ki
24±n/a nM
Citation
 Zhuang, T; Xiong, J; Ren, X; Liang, L; Qi, Z; Zhang, S; Du, W; Chen, Y; Liu, X; Zhang, G Benzylaminofentanyl derivates: Discovery of bifunctional ? opioid and ? Eur J Med Chem 241:0 (2022) [PubMed] 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50590795
Synonyms:
CHEMBL5174391
Type:
Small organic molecule
Emp. Form.:
C24H31FN2O
Mol. Mass.:
382.5141
SMILES:
CCCC(=O)N(Cc1ccc(F)cc1)C1CCN(CCc2ccccc2)CC1
Structure:
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