Reaction Details Report a problem with these data
Target
G-protein coupled estrogen receptor 1
Ligand
BDBM50590843
Substrate
n/a
Meas. Tech.
ChEMBL_2198170 (CHEMBL5110686)
Ki
11±n/a nM
Citation
 Khan, MZI; Uzair, M; Nazli, A; Chen, JZ An overview on Estrogen receptors signaling and its ligands in breast cancer. Eur J Med Chem 241:0 (2022) [PubMed] 
Target
Name:
G-protein coupled estrogen receptor 1
Synonyms:
CEPR | CMKRL2 | DRY12 | G-protein coupled estrogen receptor 1 | G-protein-coupled receptor (GPR30 ) | GPER | GPER1 | GPER1_HUMAN | GPR30
Type:
PROTEIN
Mol. Mass.:
42259.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_982507
Residue:
375
Sequence:
MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV
  
Inhibitor
Name:
BDBM50590843
Synonyms:
CHEMBL5170710
Type:
Small organic molecule
Emp. Form.:
C21H18BrNO3
Mol. Mass.:
412.277
SMILES:
[H][C@]12CC=C[C@@]1([H])c1cc(ccc1NC2c1cc2OCOc2cc1Br)C(C)=O |r,c:3|
Structure:
Search PDB for entries with ligand similarity: