Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50557186
Substrate
n/a
Meas. Tech.
ChEMBL_2210234 (CHEMBL5123183)
Ki
6.5±n/a nM
Citation
 Bechthold, E; Schreiber, JA; Ritter, N; Schepmann, D; Daniliuc, C; Seebohm, G; Wünsch, B Synthesis and biological evaluation of conformationally restricted GluN2B ligands derived from eliprodil. Eur J Med Chem 237:0 (2022) [PubMed] 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50557186
Synonyms:
CHEMBL493054
Type:
Small organic molecule
Emp. Form.:
C21H27NO2
Mol. Mass.:
325.4446
SMILES:
C[C@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 |r|
Structure:
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