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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50168212
Substrate
n/a
Meas. Tech.
ChEMBL_304206 (CHEMBL829746)
EC50
1700±n/a nM
Citation
 Sun, CL; Pang, RF; Zhang, H; Yang, M Design, synthesis, and biological evaluation of novel 4-hydroxypyrone derivatives as HIV-1 protease inhibitors. Bioorg Med Chem Lett 15:3257-62 (2005) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50168212
Synonyms:
3-(2-Ethyl-phenylsulfanyl)-4-hydroxy-6-naphthalen-1-ylmethyl-6-propyl-5,6-dihydro-pyran-2-one | CHEMBL190556
Type:
Small organic molecule
Emp. Form.:
C27H28O3S
Mol. Mass.:
432.574
SMILES:
CCCC1(Cc2cccc3ccccc23)CC(=O)C(Sc2ccccc2CC)C(=O)O1
Structure:
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