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Target
Adenosine receptor A2a
Ligand
BDBM50011294
Substrate
n/a
Meas. Tech.
ChEMBL_2213693 (CHEMBL5126825)
Ki
3.4±n/a nM
Citation
 Saini, A; Patel, R; Gaba, S; Singh, G; Gupta, GD; Monga, V Adenosine receptor antagonists: Recent advances and therapeutic perspective. Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50011294
Synonyms:
A2A | Ro-4494351 | Ro-4494351-002 | Ro-4494351000 | SYN-115 | TOZADENANT
Type:
Small organic molecule
Emp. Form.:
C19H26N4O4S
Mol. Mass.:
406.499
SMILES:
COc1ccc(N2CCOCC2)c2sc(NC(=O)N3CCC(C)(O)CC3)nc12
Structure:
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