Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50259304
Substrate
n/a
Meas. Tech.
ChEMBL_2213714 (CHEMBL5126846)
IC50
187±n/a nM
Citation
 Saini, A; Patel, R; Gaba, S; Singh, G; Gupta, GD; Monga, V Adenosine receptor antagonists: Recent advances and therapeutic perspective. Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50259304
Synonyms:
CHEMBL4070079
Type:
Small organic molecule
Emp. Form.:
C26H18N4O2
Mol. Mass.:
418.4467
SMILES:
O=C(N(C(=O)c1ccccc1)c1nccn2cc(nc12)-c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: