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Target
Adenosine receptor A2a
Ligand
BDBM50493145
Substrate
n/a
Meas. Tech.
ChEMBL_2213746 (CHEMBL5126878)
Ki
0.004200±n/a nM
Citation
 Saini, A; Patel, R; Gaba, S; Singh, G; Gupta, GD; Monga, V Adenosine receptor antagonists: Recent advances and therapeutic perspective. Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50493145
Synonyms:
CHEMBL2419149
Type:
Small organic molecule
Emp. Form.:
C17H10BrN3S2
Mol. Mass.:
400.315
SMILES:
Brc1ccc(\C=N\c2c(sc(=S)n2-c2ccccc2)C#N)cc1
Structure:
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