Reaction Details Report a problem with these data
Target
P2Y purinoceptor 12
Ligand
BDBM50594682
Substrate
n/a
Meas. Tech.
ChEMBL_2213851 (CHEMBL5126983)
IC50
2.8±n/a nM
Citation
 Al-Najjar, BO; Saqallah, FG; Abbas, MA; Al-Hijazeen, SZ; Sibai, OA P2Y Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50594682
Synonyms:
CHEMBL5196387
Type:
Small organic molecule
Emp. Form.:
C36H45N6O8P
Mol. Mass.:
720.7517
SMILES:
CCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CP1(=O)OCc2cccc(C)c2O1)NC(=O)c1cc(nc(n1)-c1ccccc1)N1CC[C@@H](C1)OC |r|
Structure:
Search PDB for entries with ligand similarity: