Reaction Details Report a problem with these data
Target
P2Y purinoceptor 12
Ligand
BDBM50594688
Substrate
n/a
Meas. Tech.
ChEMBL_2213851 (CHEMBL5126983)
IC50
1.000000±n/a nM
Citation
 Al-Najjar, BO; Saqallah, FG; Abbas, MA; Al-Hijazeen, SZ; Sibai, OA P2Y Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50594688
Synonyms:
CHEMBL5192953
Type:
Small organic molecule
Emp. Form.:
C27H39N6O7PS
Mol. Mass.:
622.673
SMILES:
CCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CP(O)(O)=O)NC(=O)c1nc(sc1N1CCN(C)CC1)-c1ccccc1 |r|
Structure:
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