Reaction Details Report a problem with these data
Target
P2Y purinoceptor 12
Ligand
BDBM50594691
Substrate
n/a
Meas. Tech.
ChEMBL_2213855 (CHEMBL5126987)
IC50
0.330000±n/a nM
Citation
 Al-Najjar, BO; Saqallah, FG; Abbas, MA; Al-Hijazeen, SZ; Sibai, OA P2Y Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50594691
Synonyms:
CHEMBL5176593
Type:
Small organic molecule
Emp. Form.:
C23H24N6O2
Mol. Mass.:
416.4757
SMILES:
CCOC(=O)c1cc(C#N)c(nc1C)N1CCC(CC1)c1nnc([nH]1)-c1ccccc1
Structure:
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