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Target
Dual specificity protein phosphatase 22
Ligand
BDBM50168873
Substrate
n/a
Meas. Tech.
ChEMBL_305310 (CHEMBL831701)
IC50
59000±n/a nM
Citation
 Cutshall, NS; O'Day, C; Prezhdo, M Rhodanine derivatives as inhibitors of JSP-1. Bioorg Med Chem Lett 15:3374-9 (2005) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 22
Synonyms:
DUS22_HUMAN | DUSP22 | Dual specificity phosphatase 22 | Dual specificity protein phosphatase (MKPX) | Dual specificity protein phosphatase 22 | Dual specificity protein phosphatase 22 (VHX) | Dual specificity protein phosphatase VHX (VHX) | JSP1 | LMWDSP2 | MKPX | Mitogen-activated protein kinase phosphatase x | VHX
Type:
Protein
Mol. Mass.:
20915.83
Organism:
Homo sapiens (Human)
Description:
Q9NRW4
Residue:
184
Sequence:
MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAFLRRL
  
Inhibitor
Name:
BDBM50168873
Synonyms:
3-[4-Oxo-5-prop-(Z)-ylidene-2-thioxo-thiazolidin-3-yl]-benzoic acid | CHEMBL359646
Type:
Small organic molecule
Emp. Form.:
C13H11NO3S2
Mol. Mass.:
293.361
SMILES:
CC\C=C1/SC(=S)N(C1=O)c1cccc(c1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: