Reaction Details Report a problem with these data
Target
Basic phospholipase A2 1
Ligand
BDBM50169759
Substrate
n/a
Meas. Tech.
ChEMBL_305607 (CHEMBL828145)
IC50
98000±n/a nM
Citation
 Khanum, SA; Murari, SK; Vishwanth, BS; Shashikanth, S Synthesis of benzoyl phenyl benzoates as effective inhibitors for phospholipase A2 and hyaluronidase enzymes. Bioorg Med Chem Lett 15:4100-4 (2005) [PubMed]  Article 
Target
Name:
Basic phospholipase A2 1
Synonyms:
PA2B1_NAJME | Phospholipase A2 isozyme DE-I
Type:
PROTEIN
Mol. Mass.:
13475.55
Organism:
Naja melanoleuca
Description:
ChEMBL_305607
Residue:
118
Sequence:
NLYQFKNMIHCTVPNRPWWHFANYGCYCGRGGKGTPVDDLDRCCQIHDKCYDEAEKISGCWPYIKTYTYESCQGTLTCKDGGKCAASVCDCDRVAANCFARATYNDKNYNIDFNARCQ
  
Inhibitor
Name:
BDBM50169759
Synonyms:
2-Methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester | 4-methyl-2-(2-methylbenzoyl)phenyl 2-methylbenzoate | CHEMBL189359
Type:
Small organic molecule
Emp. Form.:
C23H20O3
Mol. Mass.:
344.4031
SMILES:
Cc1ccc(OC(=O)c2ccccc2C)c(c1)C(=O)c1ccccc1C
Structure:
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