Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50595382
Substrate
n/a
Meas. Tech.
ChEMBL_2216591 (CHEMBL5129723)
Kd
13500±n/a nM
Citation
 Shepherd, C; Robinson, S; Berizzi, A; Thompson, LEJ; Bird, L; Culurgioni, S; Varzandeh, S; Rawlins, PB; Olsen, RHJ; Navratilova, IH Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding Fragments. ACS Med Chem Lett 13:1172-1181 (2022) [PubMed] 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50595382
Synonyms:
CHEMBL5208068
Type:
Small organic molecule
Emp. Form.:
C14H12ClNO3S
Mol. Mass.:
309.768
SMILES:
CS(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(Cl)c1
Structure:
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