Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50275499
Substrate
n/a
Meas. Tech.
ChEMBL_2216599 (CHEMBL5129731)
Kd
280±n/a nM
Citation
 Shepherd, C; Robinson, S; Berizzi, A; Thompson, LEJ; Bird, L; Culurgioni, S; Varzandeh, S; Rawlins, PB; Olsen, RHJ; Navratilova, IH Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding Fragments. ACS Med Chem Lett 13:1172-1181 (2022) [PubMed] 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50275499
Synonyms:
2-(4-fluorophenyl)-3-(4-pyridinyl)pyrazolo-[1,5-a]pyridine | CHEMBL485745
Type:
Small organic molecule
Emp. Form.:
C18H12FN3
Mol. Mass.:
289.3064
SMILES:
Fc1ccc(cc1)-c1nn2ccccc2c1-c1ccncc1
Structure:
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