Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50170351
Substrate
n/a
Meas. Tech.
ChEMBL_302853 (CHEMBL828769)
Ki
570±n/a nM
Citation
 Huffman, JW; Szklennik, PV; Almond, A; Bushell, K; Selley, DE; He, H; Cassidy, MP; Wiley, JL; Martin, BR 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett 15:4110-3 (2005) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50170351
Synonyms:
1-(1-Pentyl-1H-indol-3-yl)-2-p-tolyl-ethanone | 1-(1-pentyl-1H-indol-3-yl)-2-p-tolylethanone | CHEMBL187354 | JWH-208
Type:
Small organic molecule
Emp. Form.:
C22H25NO
Mol. Mass.:
319.44
SMILES:
CCCCCn1cc(C(=O)Cc2ccc(C)cc2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: