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Target
Adenosine receptor A2b
Ligand
BDBM50170949
Substrate
n/a
Meas. Tech.
ChEMBL_306686 (CHEMBL830020)
IC50
>1000±n/a nM
Citation
 Baraldi, PG; Tabrizi, MA; Preti, D; Bovero, A; Fruttarolo, F; Romagnoli, R; Zaid, NA; Moorman, AR; Varani, K; Borea, PA New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. J Med Chem 48:5001-8 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50170949
Synonyms:
2-(4-Fluoro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one | CHEMBL363516
Type:
Small organic molecule
Emp. Form.:
C16H10FN3O
Mol. Mass.:
279.2685
SMILES:
Fc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O
Structure:
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