Target
Adenosine receptor A1
Ligand
BDBM50170947
Substrate
n/a
Meas. Tech.
ChEMBL_303560 (CHEMBL828960)
Ki
>1000±n/a nM
Citation
 Baraldi, PGTabrizi, MAPreti, DBovero, AFruttarolo, FRomagnoli, RZaid, NAMoorman, ARVarani, KBorea, PA New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. J Med Chem 48:5001-8 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50170947
Synonyms:
2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-thione | CHEMBL187842
Type:
Small organic molecule
Emp. Form.:
C16H11N3S
Mol. Mass.:
277.344
SMILES:
S=c1[nH]c2ccccc2c2nn(cc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: