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Target
Carbon storage regulator
Ligand
BDBM50596606
Substrate
n/a
Meas. Tech.
ChEMBL_2221538 (CHEMBL5134872)
IC50
48100±n/a nM
Citation
 Jakob, V; Zoller, BGE; Rinkes, J; Wu, Y; Kiefer, AF; Hust, M; Polten, S; White, AM; Harvey, PJ; Durek, T; Craik, DJ; Siebert, A; Kazmaier, U; Empting, M Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA. Eur J Med Chem 231:0 (2022) [PubMed] 
Target
Name:
Carbon storage regulator
Synonyms:
CSRA_ECOLI | Synonyms=zfiA | Translational dual regulator CsrA | csrA | zfiA
Type:
PROTEIN
Mol. Mass.:
6857.32
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_120766
Residue:
61
Sequence:
MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
  
Inhibitor
Name:
BDBM50596606
Synonyms:
CHEMBL5203462
Type:
Small organic molecule
Emp. Form.:
C40H56N12O11
Mol. Mass.:
880.9464
SMILES:
CC(C)C[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2cnnn2C[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)[C@@H](NC(C)=O)C(C)C |r|
Structure:
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