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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM10799
Substrate
n/a
Meas. Tech.
ChEMBL_320782 (CHEMBL884737)
Ki
17000±n/a nM
Citation
 Toprakçí, M; Yelekçi, K Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds. Bioorg Med Chem Lett 15:4438-46 (2005) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM10799
Synonyms:
(3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-ol | 6-hydroxy-N-propargyl-1(R)-aminoindan | Aminoindan deriv. (R)39u | CHEMBL371428 | R-HPAI | rasagiline analogue
Type:
Small organic molecule
Emp. Form.:
C12H13NO
Mol. Mass.:
187.2377
SMILES:
Oc1ccc2CC[C@@H](NCC#C)c2c1 |r|
Structure:
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