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Target
Mu-type opioid receptor
Ligand
BDBM50174200
Substrate
n/a
Meas. Tech.
ChEMBL_326605 (CHEMBL863386)
IC50
1600±n/a nM
Citation
 Li, T; Shiotani, K; Miyazaki, A; Fujita, Y; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y New series of potent delta-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif. Bioorg Med Chem Lett 15:5517-20 (2005) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50174200
Synonyms:
CHEMBL380590 | H-Dmt-Tic-NH-(CH2)6-NH-Tic-H
Type:
Small organic molecule
Emp. Form.:
C37H47N5O4
Mol. Mass.:
625.8002
SMILES:
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCCCNC(=O)C1Cc2ccccc2CN1
Structure:
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