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Target
Melatonin receptor type 1A
Ligand
BDBM50598930
Substrate
n/a
Meas. Tech.
ChEMBL_2228637 (CHEMBL5142150)
EC50
1.3±n/a nM
Citation
 Somalo-Barranco, G; Serra, C; Lyons, D; Piggins, HD; Jockers, R; Llebaria, A Design and Validation of the First Family of Photo-Activatable Ligands for Melatonin Receptors. J Med Chem 65:11229-11240 (2022) [PubMed] 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50598930
Synonyms:
CHEMBL5173623
Type:
Small organic molecule
Emp. Form.:
C21H21N3O6
Mol. Mass.:
411.4079
SMILES:
COc1ccc2n(cc(CCNC(C)=O)c2c1)C(=O)OCc1ccccc1[N+]([O-])=O
Structure:
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