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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM67454
Substrate
n/a
Meas. Tech.
ChEMBL_2231110 (CHEMBL5144882)
IC50
7990±n/a nM
Citation
 Lefin, R; Petzer, A; Petzer, JP Phenothiazine, anthraquinone and related tricyclic derivatives as inhibitors of monoamine oxidase. Bioorg Med Chem 54:0 (2022) [PubMed] 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Homo sapiens (Human)
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM67454
Synonyms:
1,2,4-trihydroxy-9,10-anthraquinone | 1,2,4-trihydroxyanthracene-9,10-dione | 1,2,4-tris(oxidanyl)anthracene-9,10-dione | MLS002473304 | SMR001306802 | cid_6683 | hsp90_173 | purpurin
Type:
Small organic molecule
Emp. Form.:
C14H8O5
Mol. Mass.:
256.2103
SMILES:
Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O
Structure:
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