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Target
Integrase
Ligand
BDBM50177218
Substrate
n/a
Meas. Tech.
ChEMBL_332849 (CHEMBL859228)
IC50
230000±n/a nM
Citation
 Majerz-Maniecka, K; Musiol, R; Nitek, W; Oleksyn, BJ; Mouscadet, JF; Le Bret, M; Polanski, J Intermolecular interactions in the crystal structures of potential HIV-1 integrase inhibitors. Bioorg Med Chem Lett 16:1005-9 (2006) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50177218
Synonyms:
2-((2,5-dichloro-4-nitrophenylamino)(methoxy)methyl)quinolin-8-ol | CHEMBL202291
Type:
Small organic molecule
Emp. Form.:
C17H13Cl2N3O4
Mol. Mass.:
394.209
SMILES:
COC(Nc1cc(Cl)c(cc1Cl)[N+]([O-])=O)c1ccc2cccc(O)c2n1
Structure:
Search PDB for entries with ligand similarity: