Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50600463
Substrate
n/a
Meas. Tech.
ChEMBL_2234234 (CHEMBL5148006)
IC50
0.075000±n/a nM
Citation
 Hu, S; Ma, L; Dong, B; Shan, Q; Zhou, J; Zhang, G; Wang, M; Cen, S; Zhu, M; Wang, J; Wang, Y A kind of HIV-1 protease inhibitors containing phenols with antiviral activity against DRV-resistant variants. Bioorg Med Chem 64:0 (2022) [PubMed] 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50600463
Synonyms:
CHEMBL5200970
Type:
Small organic molecule
Emp. Form.:
C27H31FN2O6S
Mol. Mass.:
530.608
SMILES:
CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(F)cc1 |r|
Structure:
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