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Target
Phospho-N-acetylmuramoyl-pentapeptide-transferase
Ligand
BDBM50600490
Substrate
n/a
Meas. Tech.
ChEMBL_2234308 (CHEMBL5148080)
IC50
24000±n/a nM
Citation
 Kusaka, S; Yamamoto, K; Shinohara, M; Minato, Y; Ichikawa, S Design, synthesis and conformation-activity relationship analysis of LNA/BNA-type 5'-O-aminoribosyluridine as MraY inhibitors. Bioorg Med Chem 65:0 (2022) [PubMed] 
Target
Name:
Phospho-N-acetylmuramoyl-pentapeptide-transferase
Synonyms:
MRAY_STAAU | mraY
Type:
PROTEIN
Mol. Mass.:
35238.55
Organism:
Staphylococcus aureus (strain MRSA252)
Description:
ChEMBL_827497
Residue:
321
Sequence:
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH
  
Inhibitor
Name:
BDBM50600490
Synonyms:
CHEMBL5200223
Type:
Small organic molecule
Emp. Form.:
C17H21N3O9
Mol. Mass.:
411.3633
SMILES:
[H][C@]12OC[C@@](O[C@H]1n1ccc(=O)[nH]c1=O)([C@@H](O[C@@H]1O[C@H](CN)[C@@H](O)[C@H]1O)C#C)[C@H]2O |r,TLB:7:6:3.2:28|
Structure:
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