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Target
Trace amine-associated receptor 1
Ligand
BDBM50181821
Substrate
n/a
Meas. Tech.
ChEMBL_332033 (CHEMBL859598)
EC50
20.2±n/a nM
Citation
 Hart, ME; Suchland, KL; Miyakawa, M; Bunzow, JR; Grandy, DK; Scanlan, TS Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. J Med Chem 49:1101-12 (2006) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50181821
Synonyms:
CHEMBL202071 | O-(p-trifluoromethyl)benzyl-tyramine
Type:
Small organic molecule
Emp. Form.:
C16H16F3NO
Mol. Mass.:
295.2995
SMILES:
NCCc1ccc(OCc2ccc(cc2)C(F)(F)F)cc1
Structure:
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