Reaction Details Report a problem with these data
Target
Fructose-bisphosphate aldolase, glycosomal
Ligand
BDBM50183272
Substrate
n/a
Meas. Tech.
ChEMBL_336152 (CHEMBL863697)
Ki
23030±n/a nM
Citation
 Dax, C; Duffieux, F; Chabot, N; Coincon, M; Sygusch, J; Michels, PA; Blonski, C Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei. J Med Chem 49:1499-502 (2006) [PubMed]  Article 
Target
Name:
Fructose-bisphosphate aldolase, glycosomal
Synonyms:
ALD | ALF_TRYBB | Fructose-bisphosphate aldoloase, glycosomal
Type:
PROTEIN
Mol. Mass.:
41192.02
Organism:
Trypanosoma brucei brucei
Description:
ChEMBL_813853
Residue:
372
Sequence:
MSKRVEVLLTQLPAYNRLKTPYEAELIETAKKMTAPGKGLLAADESTGSCSKRFAGIGLSNTAEHRRQYRALMLECEGFEQYISGVILHDETVYQKAKTGETFPQYLRRRGVVPGIKTDCGLEPLVEGAKGEQMTAGLDGYIKRAKKYYAMGCRFCKWRNVYKIQNGTVSEAVVRFNAETLARYAILSQLCGLVPIVEPEVMIDGTHDIETCQRVSQHVWSEVVSALHRHGVVWEGCLLKPNMVVPGAESGLKGHAEQVAEYTVKTLARVIPPALPGVTFLSGGLSEVMASEYLNAMNNCPLPRPWKLTFSYARALQSSAIKRWGGKESGVEAGRRAFMHRAKMNSLAQLGKYNRADDDKDSQSLYVAGNTY
  
Inhibitor
Name:
BDBM50183272
Synonyms:
5-formyl-6-hydroxy-2-naphthyl di-sodium phosphate | CHEMBL382634
Type:
Small organic molecule
Emp. Form.:
C11H9O6P
Mol. Mass.:
268.1593
SMILES:
Oc1ccc2cc(OP(O)(O)=O)ccc2c1C=O
Structure:
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