Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50602685
Substrate
n/a
Meas. Tech.
ChEMBL_2241747 (CHEMBL5155957)
Ki
224±n/a nM
Citation
 Tosh, DK; Salmaso, V; Campbell, RG; Rao, H; Bitant, A; Pottie, E; Stove, CP; Liu, N; Gavrilova, O; Gao, ZG; Auchampach, JA; Jacobson, KA A Eur J Med Chem 228:0 (2022) [PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50602685
Synonyms:
CHEMBL5174613
Type:
Small organic molecule
Emp. Form.:
C31H42N6O6
Mol. Mass.:
594.7018
SMILES:
CNC(=O)[C@@]12C[C@@H]1[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NCCc3ccc(OC)c(O)c3)nc(OCCCC3CCCCC3)nc12 |r|
Structure:
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